| PEDIGREES WITH AN AFFECTED SIB-PAIR WITH DNA AVAILABLE |
|
|
|
| # sibships, 2 affected sibs with DNA available |
536 |
238 |
468 |
| # sibships, 3 affected sibs with DNA available |
61 |
17 |
48 |
| # sibships, 4 affected sibs with DNA available |
9 |
2 |
7 |
| # sibships, 5 or more affected sibs with DNA available |
1 |
0 |
1 |
| Total # pedigrees,at least 1 affected sib-pair with DNA available |
604 |
257 |
521 |
| # affected sib-pairs with DNA available (n-1) |
689 |
278 |
589 |
| Maximum # affected sib-pairs with DNA available [n*(n-1)/2] |
783 |
301 |
664 |
| # affected sibs with DNA available |
1296 |
535 |
1113 |
| # other affected relatives with DNA available |
58 |
21 |
46 |
| Total # affecteds with DNA available |
1354 |
556 |
1159 |
| # unaffected sibs with DNA available |
68 |
31 |
73 |
| # other unaffected relatives with DNA available |
144 |
70 |
126 |
| Total # subjects with DNA available |
1566 |
657 |
1358 |
| # sibships, no parent with DNA available |
477 |
200 |
413 |
| # sibships, 1 parent with DNA available |
111 |
48 |
97 |
| # sibships, both parents with DNA available |
19 |
9 |
14 |
| # afffecteds with DNA available, by sex |
|
|
|
| Female |
655 |
237 |
583 |
| Male |
699 |
319 |
576 |
| PEDIGREES WITHOUT AN AFFECTED SIB-PAIR WITH DNA AVAILABLE |
|
|
|
| # pedigrees, one affected with DNA available |
2977 |
2005 |
2689 |
| # pedigrees, 2 affecteds with DNA available |
158 |
68 |
145 |
| # pedigrees, 3 affecteds with DNA available |
20 |
3 |
17 |
| # pedigrees, 4 affecteds with DNA available |
2 |
1 |
1 |
| # sibships, 5 or more affecteds with DNA available |
2 |
0 |
2 |
| Total # pedigrees, at least 1 affected with DNA available |
3159 |
2077 |
2854 |
| Total # affecteds with DNA available |
3372 |
2154 |
3044 |
| Total # subjects with DNA available |
3501 |
4410 |
3709 |
| TRIOS FOR ASSOCIATION ANALYSIS |
|
|
|
| (AN AFFECTED INDIVIDUAL + 2 PARENTS WITH DNA AVAILABLE) |
|
|
|
| # pedigrees containing at least 1 trio |
25 |
19 |
21 |
| INDEPENDENT CASES AND CONTROLS |
|
|
|
| # independent cases |
3763 |
2334 |
3375 |
| # potential controls from Control Sample |
0 |
0 |
0 |