Polysubstance Dependence Descriptive Table

Version 4.0 (August 2019)

DESCRIPTIVE INFORMATION BY DIAGNOSTIC MODEL

M1: DSM-IV Illicit Drug Dependence / Disorder (opioid, cocaine, cannabis, sedative, stimulant, other)

M2: DSM-IV Opioid Dependence / Disorder

M3: DSM-IV Cocaine Dependence / Disorder

M4: DSM-IV Cannabis Dependence / Disorder

M5: DSM-IV Stimulant Dependence / Disorder

M6: DSM-IV Sedative Dependence / Disorder

M7: DSM-IV Alcohol Dependence / Disorder

M8: DSM-IV Nicotine Dependence / Disorder

M1M2M3M4M5M6M7M8
PEDIGREES WITH AN AFFECTED SIB-PAIR WITH DNA AVAILABLE
# sibships, 2 affected sibs with DNA available102147713078108
# sibships, 3 affected sibs with DNA available30020048
# sibships, 4 affected sibs with DNA available10000001
# sibships, 5 or more affected sibs with DNA available00000000
Total # pedigrees,at least 1 affected sib-pair with DNA available106147913082117
# affected sib-pairs with DNA available (n-1)111148113086127
Maximum # affected sib-pairs with DNA available [n*(n-1)/2]117148313090138
# affected sibs with DNA available21728160260168244
# other affected relatives with DNA available61020080
Total # affecteds with DNA available22338162260176244
# unaffected sibs with DNA available390327602640
# other unaffected relatives with DNA available98057715087129
Total # subjects with DNA available360316266470289413
# sibships, no parent with DNA available230019201119
# sibships, 1 parent with DNA available560336704267
# sibships, both parents with DNA available210119402431
# afffecteds with DNA available, by sex
Female7814501506183
Male14524112110115161
PEDIGREES WITHOUT AN AFFECTED SIB-PAIR WITH DNA AVAILABLE
# pedigrees, one affected with DNA available77114424075616749632452
# pedigrees, 2 affecteds with DNA available8511123920610
# pedigrees, 3 affecteds with DNA available101030040
# pedigrees, 4 affecteds with DNA available00000000
# sibships, 5 or more affecteds with DNA available00000000
Total # pedigrees, at least 1 affected with DNA available86615625279816949697452
Total # affecteds with DNA available97116926484317149766452
Total # subjects with DNA available31053462344931993418346531763052
TRIOS FOR ASSOCIATION ANALYSIS
(AN AFFECTED INDIVIDUAL + 2 PARENTS WITH DNA AVAILABLE)
# pedigrees containing at least 1 trio130182712424310775
INDEPENDENT CASES AND CONTROLS
# independent cases97215725687718249779569
# independent controls in distribution file00000000